This article is a pretty good treatment of specific problems with grains: http://www.marksdailyapple.com/definitive-guide-grains/
Again, some people can be in good shape and eat grains. But if you want to be as healthy as possible they need to be avoided. Or if you're overweight/out of shape, removing them from your diet will definitely speed up the process of improving your health.
I know for my own body, it's best for me to avoid them completely. They have a very addictive quality for me, more so than anything sweet. Forget the ice cream, give me a roll!