Thanks to the 23andMe test I found out have I think 6 of 8 rare bad variants of various genes that give me what's currently estimated at around a cumulative 50% chance to develop a particular type of leukemia late in life. Of course, 23andMe doesn't provide this information - I came across it accidentally while studying my SNPs with other third party tools.

I don't really think about it that much - experimental treatments for it are already basically curing the disease and if I do get it it probably won't be for another 20 or 30 years. But now I can be the tiniest bit proactive - getting my CBC checked every few years, and watching out for unusual symptoms like fatigue.

The challenge is in communicating these things properly with fair analyses of the probability - we have X model that predicts Y risk, and we have Z error bounds on that. While it's unfortunate that most people lack the education to interpret statistical statements like that, I don't see why that should legally preclude me from getting information relevant to my health without a gatekeeper geneticist to hold my hand through "this variant has 1% prevalence, that means that 1 in a hundred people have it...".