Its supported in all regions as of January 25: https://aws.amazon.com/blogs/aws/aws-ipv6-update-global-supp...
1. You get a single IPv6 per instance (as opposed to a CIDR range).
2. You still have to deal with IPv4 CIDR ranges
3. ...which means you have to deal with all the overlaps still :(
IMO I would love it if my ec2 instances were IPv6 only, and then use public IPv4 addresses or dual stack loadbalancers as necessary for public ingress.