Pretty sure it's not a typo. Amazon i3.16xlarge is 488 GB of Ram, 64 vCPUs, and a 20 Gigabit connection. Postgres/Mysql can absolutely scream perf-wise on that.
Outside AWS, you can put 3-6 TB in a normal-ish server from Dell or HP, or 64 TB in a big iron box from Fujitsu or IBM.