Where's the district attorney? If someone is claiming the 5th because he might be incriminated that seems like pretty strong probable cause for a criminal investigation.
That being said, "where there's smoke there's fire"... but pleading the 5th isn't always the drama we see in Law and Order and Making a Murderer - often individuals just don't want to be misconstrued and prosecuted for saying something and their words being taken out of context.
https://www.washingtonpost.com/news/volokh-conspiracy/wp/201...
https://www.washingtonpost.com/news/volokh-conspiracy/wp/201...