I just installed GuixSD 0.12 last week on a Dell 13 7000. Went mostly smoothly (had to use Grub BIOS instead of UEFI, that's been fixed in 0.13) after I replaced the Intel WiFi card with an Atheros based one.

My needs are simple: emacs, Clojure (with Icedtea), Icecat and StumpWM. Plus all the guile goodness!

Just realized I'm living in a system with four Lisps front and center (guile, Common Lisp, elisp, and Clojure)