* __repr__ comes for free.
* converting all members to a list or dict comes for free.
* converting a list or dict TO a namedtuple comes for free.
* more restrictive in what you can do with data structures inside the namedtuple - may lead to a cleaner design where you think about pulling apart the data into multiple tuples at an earlier point in the prototype phase.
* You by design won't make functions into instance methods that depend on multiple data tuples.
* Need to extend a function to deal with different types of tuples? You now don't need to refactor an instance method into a first class function, instead just dispatch and be done.
* Inheritance can be solved with the above method as well. This may actually be more maintainable than class based inheritance, since you see all the logic for a specific function explicitely (or explicitely dispatched) in one place.
The only reason I can think of to still use a class: If you can heavily profit from inheritance or if you need to program against an "interface" like dict- or listlike behavior or comparison operators.