I've chosen .xyz for my personal homepage because it was cheap, new and looks nice in my opinion. As good .com domains start to become rare I think .xyz has potential to become one of the next well-known general purpose domains.
Be careful of .xyz. Recent $1 sales on .xyz have caused it to be bought by a lot of email spammers. If you also want to use it for email (not just as a website), you'll run into delivery issues.