I have a 3GS, and every time I pick up call from desk phone (with iPhone at the desk), I will experience interference. Now, I need to put my 3GS around half meter away every time there's call to office line. I wonder if anyone experience this also.
My JBL Pro speakers never have interference from my iPhone.
I have even remodeled my home to include a bedroom dedicated to my iPhone.
Totally worth it.
Does your 3GS say '3G' on the status bar while it's interfering with your speakers?