I am convinced that Agile is implicitly related to business application development, and when someone is saying he/she is using Agile methodology, they most likely develop web applications for enterprises. And probably this is the most widespread niche today. But frankly speaking, I don't think this is not the most challenging work for programmers. Been there, done that.
But I am yet to see Agile evangelist who clearly states what kind of projects Agile is appropriate for. They all speak about software development in general without making distinction, as if Linux kernel or Java virtual machine or Ruby on Rails framework should be developed with their methodology. Certainly you can come up with many more examples of successfull hi-tech projects that didn't use Agile. Ironically, these projects is what makes Agile possible at all. Millions of man-haours were invested in development of operating systems, databases, virtual machines, libraries, middleware frameworks, programming languages, protocols and so on and on. Agile developers take all this as granted and try to teach everyone else how to do software development.
Or thise evangelists simply have too narrow scope, then this ignorance annoying. Does Agile work for software projects that require heavy engineering? I don't think so.