I for example have started doing Django-based projects back in 2006, me and my other programmer co-worker were at the time I think the only Django programmers in our Eastern European country. We had also done some quite cool map mash-ups. But pretty soon after that people around us also started doing Ruby stuff, Plone/Zope (maybe not so cool, but interesting nonetheless), we had a local site that had done street photos the same as GStreetView 2 or 3 years before Google started covering our streets, some Information Retrieval/AI projects, it was not all a technological desert. And in recent years things have started becoming even more dynamic, but I have to admit I stopped paying that much attention to the local IT scene.
But, yeah, Eastern Europe (and Europe in general, with the possible exceptions of London, Berlin and maybe Dublin) will never get even close to the "feeling" one gets as a programmer in SV. In my mid- to late 20s I was pretty well aware of that I and was kind of let down, I was feeling that I was losing out by me not being in SV, but now, that I've grown a little older, I feel like I didn't lose that much by staying here.