* A lot of home conditioners are fighting the weather in conditions with poor insulation, running when nobody is home, or running in rooms when people are in different parts of the house.
* Office air conditioners are often set too cold, subjectively speaking, sometimes resulting in workers bringing sweaters or even space heaters to their desks. This is shockingly common. Multi-zone cooling can make things more uniform, and if you can get people to stop using space heaters during the summer, that can make a big difference. Gender is supposedly a huge factor in temperature preferences, and offices are set to men's cooler preferences. In some locations this is exacerbated by the fact that men wear suits and ties while the women wear skirts and weather-appropriate tops.
Personally, I want an air conditioner system that isn't set to a specific temperature, but instead reduces the extreme temperatures outside. So instead of keeping it set at 22 degrees, maybe it would be set to 22 degrees when it's 27 degrees out, but the AC goes to 25 degrees when it's 35 degrees out. I find this more comfortable, because there's less of a shock when going outside or coming inside.