https://en.wikipedia.org/wiki/Tejon_Pass - 4,160 ft
Tejon Pass is on I-5 in northern LA County, and it is a huge trucking route. The grade is very steep between the Central Valley and the top of the pass, and is fairly challenging for trucks. There is no equivalent to those conditions in PA.
Also, if your impression of Tahoe is only the heavily touristed parts, your view is incomplete. The mountain roads in the Sierras have no equivalent east of the Mississippi.