Substitute "on a plane" for "on a train" and you'd be correct. Trains are great for bringing a laptop and getting work done while you travel: the seats have reasonably generous space, there's power outlets (many planes still don't have these in economy), and you're allowed to get your laptop out as soon as you sit down, well before the train even leaves the station, and you don't have to put it away until you're ready to get up and walk off the train.
Even with a faster turnpike, Pittsburgh is well outside the Northeast Corridor megalopolis which does have an isolating effect on capital, and even with a tech makeover, it's still going to be an isolating city without similar makeovers in eastern Ohio and upstate NY.
I'm of that era of CMU grad the article talks about that spent four years there and left. It's a great town and I enjoy going back, but the prime reason I didn't stick around was isolation.