The things that didn't were typically lesser used desktoppy things or more community written software that didn't take endianness into consideration. If you're not afraid to dig into sources alot of things only took adding an endianness hack / byteswap to certain lines to make things work properly.
Also to check into are some languages/compilers/interpreters simply might not have a backend for your CPU. If you use any of these critically you might double check; common things like perl/python/java/ruby should be fine.
I'd expect most server-side / computation oriented things should be fine- desktop, etc, not so sure especially since noone is making any power based workstations these days, though remote GUI mgmt is still useful in some annoying cases
Overall stability, barring per-platform issues should be fine as well.
basically, if you don't mind getting your hands a bit dirty from time to time, it should be okay; not sure of support for this particular board / firmware/ etc though..
hopefully someone with recent experience can confirm