Foreknowledge of all that wasn't enough to keep me from working at the job for a while. It was a super interesting experience, and I learned an enormous amount about biochem, comp bio, synthetic bio, and several other fascinating subjects.
What eventually caused me to leave was the continuous, losing battle for sane software development practices. It wasn't just that lab: everyone I encountered in the techy side of bio - save for the oddball comp bio or synth bio prof/student with a CS background that included industry experience - was completely adverse to treating their software as anything other than a means to an end. In the year and a half I lasted before taking a job in industry, that one lab easily wasted hundreds of work hours navigating easily preventable tech debt, writing the exact same code for the Nth time, fixing the same deployment or revision control mistakes for the Nth time, etc, while any attempt on my part to put in standards and practices to alleviate any of it was dismissed out of hand as a waste of time.
In short, I agree that there's a shortage of software engineering knowledge and skills in the field, but beyond the obvious financial, organizational, and career development hurdles keeping talent away, there's a major attitude adjustment required by the researchers themselves.