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Would it be okay to point out that he's fat if he was overweight? Pointing out a negative fact unrelated to the topic like this is a rude thing to do.

"Hey, it's true" but it doesn't really add any useful information, it's just mean.

It might be factual, but the mention of cat urine smell is unnecessary and rude.

You're right, but it's a totally irrelevant fact that other people will still judge on.