Starting a startup. Honestly, the lack of control I felt at interviewing at the top tech firms back in college and my only average GPA was a big motivator for me to start my own business. I hated the idea that my career was out of my control and would depend on whether I could answer challenging interview questions under stress or my GPA/school. This was also at the peak of the ridiculous mythical word problems Microsoft, Google, et al were known for, and those were not my forte whatsoever.
Best decision I ever made