This article relates to one of my crazier recurring thoughts. Looking at how most of us have readily shifted to or accepting of virtual experiences and Baudrillard type "simulacra", I can't help but run the clock 250 years forward to see people willingly living with their brains permanently wired into an artificial reality (or, if we "crack" consciousness, being converted into conscious computer programs of sorts).
No longer would fighting the laws of physics be necessary, you could merely play a futuristic, hyperreal version of EVE Online in what your brain would identify as "reality" and do whatever you like.
But ultimately, I think we're guided by our minds and feelings. If we get the ability to keep a brain in a post-orgasmic-esque level of satisfaction and inactivity for perpetuity, it's probably game over for humanity.