He is, by far, the worst speller I know. Even after 20+ years of online conversation, I can barely understand what he's saying sometimes.
He also passes bits of professional writing past me for validation, usually to check his intent. His professional writing is always perfectly spelled, with impeccable grammar. He relies heavily on both software and human checks (secretaries and copywriters) to insure the basic quality of his writing. That's one reason why a truly wretched speller makes more in bonuses alone than I make in salary.
So yes, I have a hard time forgiving a misspelled resume. If he can do it, you can do it, too.