> alcohol deaths are a much lower percentage of the drinking population than opioid deaths are to opioid users
Unlike alcohol and tobacco, a lot of opioid use is illegal, and a lot is prescribed by doctors - this makes for a very different playing field.
If opioids were legally and openly sold, it would likely have a big impact (I'm not saying they should be, BTW).
Regulation would mean quality control, so you'd be much more likely to get what you thought you were buying.
Another example, if choice was available, almost no recreational opioid user would choose fentantyl or some of the random opioid RCs that pop up, instead opting for safer versions.