They can be prone to thinking that if someone disagrees with them, the person is just stupid or doesn't know enough. It can be very challenging to get smart people from very different domains to collaborate effectively because both sides may throw their hands up quickly and assume the other side is just dumb.
Getting smart people with very different world views to really communicate in a meaty and respectful fashion can be challenging. Both sides may be quick to dismiss the other as both wrong and stupid.