I would find frequent cases where my system would stall for 10-20s (could not caps lock toggle, pointer stopped moving). I almost always have just Chrome and gnome-terminal open (Ubuntu 16.04). I had attributed it to either a hardware or BIOS/firmware defect.
Now, after switching to Firefox I have gone a week without seeing those stalls.
YMMV -- I never bothered to investigate, it could be something as simple as slightly-less-memory-consumption from FF, or still a hardware defect that FF doesn't happen to trigger.