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Yah like doing 25k a day. That could cause problems.

Surprisingly few problems. Wife has been doing 80k a day for the past few years and have help tremendously with her auto immune decease.

If you're going to do high doses, stay away from anything with significant amount of calcium in your food (dairy, nuts etc)

80,000 IU is a terrifying number for daily intake. Did you mean 8k and not 80k?

I meant 80k. See studies from Dr Cicero Coimbra for more background if you're interested.