I would not be surprised to see MS introduce a dockerized '16bit compatibility' mode for Enterprise versions of windows. The only reason 32bit windows is still around is to support 16bit apps for these companies.
[1] https://www.microsoft.com/en-nz/download/details.aspx?id=800... [2] https://en.wikipedia.org/wiki/Windows_Virtual_PC
Pretty sure it's also used in some Atom tablets.