No personal files - music, ebooks, videos
Slavishly tied to Apple appstore.
ITunes requirement in the past
Useless Apple iCloud which cannot be trusted in the event of disaster (no retention policy)
Proprietary chargers
Many Android apps are more mature and have more features than iPhone equivalents.
Pricing Of handsets.
Slow handsets after 1.5 years, due to amongst others planned obsolence.