The price to performance is insanely good. I'm on an x370 desktop, with 2xrx550 and rx560. I'm using it as a virt/dev host. I have 16 docker instances running on the host os (Arch Linux).
Then 3 vms with PCI pass through. One for windows gaming/development. Until about three weeks back I was getting a solid 60fps @ 1080p on high across most games, but recently it's been down below 10fps. The next VM is a Linux developer desktop. Lastly, an emulator box connected to a projector away from my desk.
To switch between I just have dongles, 1xhdmi and 1xusb, behind my keyboard, and alternate the plugs. I did this because I couldn't find a good hdmi kvm that did 4k above 60hz.
This year has really been amazing for enthusiasts.