From a mere "observation" stand point along the lines "behaviorism," well almost all animals including insects "suffer" and "feel pain" because they react to violent stimuli. So, that means we probably can't from your line in the sand hurt almost any mammal or insect. That seems a little extreme doesn't lead to a very pleasant life for more aware species like you and your friends. If you want to live like that, go ahead, but I don't think you have the right to impose that on other humans, who would find living like that extremely difficult.
I personally don't have definite line in the sand. I love rabbits (for I raised rabbits when I was a kid) and most rodents and wouldn't want to see them get hurt, but I used to have rat issues in my apartment, I had to kill them otherwise I'd be constantly sick, and that would impact people who I love and I need to be there for. I owe love to people I know before rodents. And for humans I don't know, would I fight for children on the east side of my city getting sick due to lead in the water? Yes, and before crying for the suffering of rats, cows, chickens, etc.