I don't use anything but web mail (Fastmail) since 2002. I do my banking and email in one browser and my general browsing in a very locked down Firefox (Many about:config hacks, uBlock Origin, Decentraleyes, Webmail Ad Block, Privacy Badger, and No Coin) that blocks about everything save the actual content. I also run a Pi-hole. Keeping your actions compartmentalised keeps your privacy better controlled. Nothing is perfect, but keeping things separated is generally a better idea than not doing so.