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If you like this line of reasoning, Thomas Kuhn's "The Structure of Scientific Revolutions" [1] is a great academic approach to the same epistemological questions, applied to the academic community, and with some very bold conclusions about knowledge as a whole.

1. http://en.wikipedia.org/wiki/The_Structure_of_Scientific_Rev...

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I went through that book in a Philosophy of Science class, and I too recommend it. I also recommend the class, if you get a chance.

I think it is important for all scientists to understand the history of science and even spend some time thinking about the cultural/societal problems that hamper scientific progress currently.

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