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Comment by GunlogAlm | Hacker News Reader

Correct me if I'm wrong, but don't the vast majority of cases of hypercalcaemia caused by excessive D consumption involve daily doses of 40-50,000 IU? I'm sure I've read this before. If 20,000 IU is high, 50,000 IU must be enormous, so I too would very much doubt 2,000 is 'high'.

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For reference, i was on a 50k IU dose of D3 last year for schools of months. It's considered therapeutic for diagnosed and lab-confirmed deficiency.

Since then I've periodically stayed on s 10k IU supplement three times a week. That's just over the counter.

Do you take vit K and magnesium to compensate possible side effects?

I take a daily multivitamin that supplements those.

did a doctor prescribe the 10ks? that seems high compared to what I was suggested for a lab confirmed deficiency. Someone I know with a severe deficiency was prescribed very high levels only for a month or so.

I've had doctors prescribe 10k IU vitamin D. Mine was really low and i have auto-immune thyroiditis. Vitamin D works really well for auto-immune disease for me. It has gone.

10k IU is available OTC, so its not a prescription, but I do take it on my doctor's recommendation. I don't get a lot of sun, especially in the winter, and I've had chronic deficiency of D3, so I supplement at higher levels than what I'd get in your average multivitamin. 50k IU is what I was prescribed for two months to get me above the minimum recommended blood levels, and it barely did that.

I do also get my D3 levels checked annually as well, as should anyone with a diagnosed deficiency.

It very much depends. There are genes having a strong influence on vitamin D metabolism, and there are people for whom 5k I.U. are too much. (Essentially, they are metabolizing D3 into calcitriol and the other form I keep forgetting too fast)

50,000 IU is typically taken on a 1-4 week interval. Being in renal failure, I myself take it once a month and increase to twice per month in the winter.

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