CICO is not exactly true. Not all calories are equal. Fat calories, for example, are much less absorbed by the body than carbohydrates.
If you think obesity is due to the difference between 80 calories or so, you have other drastic immediate concerns (the terrible mental model being one). People aren't becoming obese because their body isn't "processing" fat calories compared to carb calories, they are obese because people eat obscene amounts of food daily.
Countries like France and Italy eat massive amounts of carbs in their diets and they don't have obesity issues on the scale of the United States.
CICO is empirically vacuous.