Economists' objective is to collect observations and use that to build predictive theories. Therefore in intent (and largely in method, depending on the area of economy) they are exactly like scientists. Whether they are successful at it or not is another question.
In practice economists guess a lot, as do priests and research scientists, and many other people. (Clarification: I use here "research scientists" to distinguish them from people who have been trained as scientists but in their day-to-day don't really occupy themselves with questions with unknown answers. Of course, those people don't guess at all. They are usually either teacher/professors or engineers.)