Best thing I want to get out of OpenAI right now is 10v10 Dota 2 Pros versus Bots All-star match. Wonder if they got anything out of last year's data from all the pros playing with their bot...
Also, aim doesn't matter as much, so you wouldn't have to introduce some artificial restrictions. (Reaction time does give you a big advantage, though. You can counter a lot of things simply by reacting to voicelines in time.)