PBS Space Time and Eons are both awesome:
* PBS Space Time, covers cosmology and quantum physics:
https://www.youtube.com/channel/UC7_gcs09iThXybpVgjHZ_7g
* PBS Eons, for geology and paleontology:
https://www.youtube.com/channel/UCzR-rom72PHN9Zg7RML9EbA
* Smarter Every Day, Destin's enthusiasm is contagious:
https://www.youtube.com/user/destinws2
* Extra Credits various topics (video game design, History, and recently history of Sci-Fi) are great:
https://www.youtube.com/user/ExtraCreditz
* Today I Found Out is just on this side of clickbaity, and is this age's "Ripley's Believe It Or Not", but still interesting and more importantly well researched:
https://www.youtube.com/user/TodayIFoundOut
* Crash Course, of course:
https://www.youtube.com/channel/UCX6b17PVsYBQ0ip5gyeme-Q
* Gaming Historian, for some insight into the making of systems that formed my (and earlier) childhood:
https://www.youtube.com/channel/UCnbvPS_rXp4PC21PG2k1UVg
* Minute Physics, whose latest few videos made Special Relativity understandable to this peon:
https://www.youtube.com/user/minutephysics/videos
* Practical Engineering, for some insight into civil engineering topics that we take for granted:
https://www.youtube.com/channel/UCMOqf8ab-42UUQIdVoKwjlQ
* Real Engineering, for insight into various other mechanical engineering topics:
https://www.youtube.com/channel/UCR1IuLEqb6UEA_zQ81kwXfg
* Standup Maths, host Matt Parker was the first to make maths approachable for me again (before 3Blue1Brown took the lead):
https://www.youtube.com/channel/UCSju5G2aFaWMqn-_0YBtq5A
* Steve Mould, who covers various topics both mathematical and physical. You may have seen that gif of him demonstrating the "levitating" siphoning "pearl necklace" (also a friend of Matt Parker, above):
https://www.youtube.com/channel/UCEIwxahdLz7bap-VDs9h35A
* The 8-Bit Guy, for some history of early home computer systems:
https://www.youtube.com/channel/UC8uT9cgJorJPWu7ITLGo9Ww
* Numberphile, the second-greatest math channel (after 3Blue1Brown), whose recent video finally made me take the Golden Ratio seriously, rather than an architectural gimmick/conspiracy theory:
https://www.youtube.com/user/numberphile
* Mathologer, another good math channel (but I must sheepishly admit I prefer 3Blue1Brown... sensing a pattern here?):
https://www.youtube.com/channel/UC1_uAIS3r8Vu6JjXWvastJg
* Periodic Videos, for chemistry and physics, often featuring the iconic Dr Martyn Poliakoff:
https://www.youtube.com/channel/UCtESv1e7ntJaLJYKIO1FoYw
* NileRed, for some homegrown chemistry, I particularly appreciate the candor of the approach and results:
https://www.youtube.com/user/TheRedNile
Not quite as much "educational", but still very very good:
* Every Frame A Painting, now finished, but a great explanation of what makes good cinematography:
https://www.youtube.com/channel/UCjFqcJQXGZ6T6sxyFB-5i6A
* NoClip, long-form documentaries about the making-of video games. Danny O'Dwyer is a treasure:
https://www.youtube.com/channel/UC0fDG3byEcMtbOqPMymDNbw
Apologies for the link spam, this list turned out longer than I expected as I went down my subscriptions, and I've probably missed a few worthy ones!
Edit the final: I discovered many of these channels through referrals from others I was watching, including from the twitter feeds of the authors. Turns out the educational landscape on YouTube is a well-connected graph!