Read "Your Money or Your Life." It will help you clarify your thinking on the job front. Some people I know use it as a spark to change their situation. Others find it helps them find peace where they are.
Most of all: you have a lot going on with you right now. If you can find a way to carve out time to do something for yourself and by yourself that can help make the hard parts of your life seem less insurmountable. Try offering the same to your wife. She may be just as depressed as you are and that is part of the nagging.
Lastly, don't worry about the less than a year thing. People understand sometimes things don't work out. When you interview for other jobs don't say why it was awful, just say it wasn't a good fit and have some innocuous reasons to hand for why that was. Preferably some things which your new employer would be doing differently.
It sounds like you have a lot to offer once you figure out where you want to go towards, not just away from.