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I would suggest you do not use your personal failures and frustrations as justification to call other researchers work a waste of time. Please go ahead and explain to us how their contribution to science is a waste of time and money (you could for example contrast it with your own accomplishments).

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There is nothing complicated about this problem: Discovering that an aspect of human cells/tissue plays a role in any aspect of human health is a waste of time because we already know this is true to begin with. Nothing has been learned.

Now I am sure there is some other info in these papers that may be useful about how the nucleolus changes with age, etc but, like the OP noted, the headlines are all about "playing a role".

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