Leaseholds often excludes business activities as does home insurance.
Does that mean it doesn't allow 100% remote work (where you always work from home but are an employee)?
Obviously the liabilities vary, if you're doing prototyping of fireworks in your garage then it's a little more risky than coding!
Insurance isn't always priced solely by risk; work-from-home insurance probably reduces claims for many people but that doesn't mean you can't charge more for it.
It would be interesting to know how occupier presence varies with claims made.