It was well known all along that humans are poorly equipped to remain actively engaged in situations that require split-second reactions, while exerting zero effort or control for hours on end.
Air traffic is as safe as it is because the accident analysis always pushes past "pilot error" as the root cause. If one pilot can make the error, why won't another? Did the system set them up to fail? Even if it didn't, could the system be enhanced such that the failure (or class of failures) could be prevented?
In the case of the human in Uber's self-driving car, they were set up for failure. And in such a well known way that makes any claim Uber was not negligent very hard to defend.