Ah, I see what you're getting at. It'd be better if the URL for get_upload_url (I think that's what the API was called) could be calculated client side.
At the moment, you're probably still more at risk of downloading a malicious library from PyPi or npm but this is sure to turn up in a CTF at some point - even curl is technically vulnerable.
Have you talked to anyone from Backblaze about this?