I think there are a few other major problems, but I think many apps are unlikely to hit them in the same way that they are unlikely to have integration issues with native code, because they don't need much native code.

Most apps only need to be a bunch of table views and detail views, with some forms. Line of business apps that need to be efficient (not pretty) or that don't use many of the advanced platform features, short lived apps for events/marketing/competitions/etc, apps for restaurants or shops, these are all places where I think React Native fits perfectly.

However, if you want your app to have the best performance (spoiler alert, you probably don't), you want to be at the cutting edge of platform support, or you want to create experiences that fit on the target platform perfectly, then I think native is the way to go. Most apps do not need this.