Same with "-2 + 2". Maybe it is loading its calculator implementation in JavaScript (including all dependencies).
Some sort of conflict between the "ignore keyword using hyphen prefix" and the "is it a calculation" detection, causing the search itself to time out and produce zero results? Searching with quotes ("2 * -2") is fast ("About 25,270,000,000 results (0.49 seconds)") but no calculator is shown.