1) Regulations by default should be capped at organization size or industry. Minimum wage is a great example of this, great for 25% of companies/industries, terrible for the rest - its hard to measure jobs that are never created as a result.
2) A powerful, well financed agency whose mandate is to audit all regulations, monitor and capture data regarding it's function, and review their ultimate utility to society as a whole. The vast majority of harmful regulations were designed in a different era and for a different evolved market. Markets also adapt to regulations as well naturally reducing utility.
This agency would have the power to temporarily end regulations until congress reviews it and either updates it or ends it officially.
3) Time limits on regulations forcing them to be renewed every x years, requiring data to show it's helping, not harming society