First, he poisons the well by talking about "integrity" and "intellectual honesty". This is a bad move at the beginning of a speech because it is far too easy to take it such that people with different conclusions are lacking in those qualities. Given his delivery, I suspect that he might actually believe that. It would be better if he just owned that this was his opinion and delivered it respectfully.
Second, the section on academic priorities was weak. He spent a large portion of the talk highlighting the mission statements of various languages, which is marketing language. But if Scala made no other changes other than its marketing language, it would not solve the problems he was highlighting. I thought too much time was spent on that part of the talk. There's another moment later in his rushed conclusion where he made stronger points that could have been fleshed out - how the academic influence leads to theoretical features that later get abandoned when the academic project is completed. (And I quite liked his revised marketing statement for Scala.)
I also didn't like that he brought up Cats vs scalaz as a flaw with the community, given that it became clear later in the talk that he had a clear bias on which was preferable. That seemed needlessly provocative.
I think the final conclusion of abandoning the OO path was interesting and fun to think about! I don't know if there's already an opinionated compiler plugin that discourages the more OO techniques while encouraging FP techniques, but I can see how that would be a lot of fun to play with, and educational in the same way that static analysis tools are. (I don't understand why "partial functions" was crossed out as something to abandon, though.)