This failure mode, at least, is already accounted for by sharding data across cabinets:
Each file is stored as 20 shards: 17 data shards and 3 parity shards. Because those shards are distributed across 20 storage pods in 20 cabinets, the Vault is resilient to the failure of a storage pod, or even a power loss to an entire cabinet.
https://www.backblaze.com/blog/vault-cloud-storage-architect...
However, they don't seem to offer multi-datacenter (or multi-region) redundancy so are still susceptible to a datacenter fire/failure.
In comparison, AWS S3 distributes data across 3 AZ's (datacenters), and you can further replicate across regions if you choose. Though you pay for that added redundancy in 3 - 4X higher cost.