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Comment by alexandercrohde | Hacker News Reader

So I've experimented consistently with pure CBD (0 THC. Even 16:1 CBD:THC is too much for me). In my opinion, it's better than weed, at least for those of us who are more sensitive to marijuana than most (e.g. I probably couldn't drive high).

I'm not saying I put it in my coffee every morning, but the relaxing effect is real and powerful. Certainly a better substance than alcohol for taking the edge off in my opinion.

You could probably write software while on CBD. If I had to characterize the effects, I'd say it makes one less intense, more patient, cures headache, and gives warm-fuzzies for a few hours. The following day you may be slightly more irritable than average though.

(Note in NYC you can sometimes get it over the counter in some head shops. In SF you can get it with a medicinal card)

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We legalized all cannibis products this year in CA. So no need for a card, and in the Bay Area delivery services will show up faster than Ubers.

Possession of cannabis is still a felony in California, as well as all 49 other states.

After recreational legalization here in CA I've been using the Dosist pens with varying success. The first one I bought was the Calm pen [0] and have been attempting to use it for things like headaches, muscle aches, and just general relaxation. Unfortunately, it never really worked for any of those use cases, not in the same way Tylenol would. What has been extremely effective for me is the Relief pen [1] which is something I use to fall asleep (think onset insomnia). Using the pen itself doesn't cause you to be sleepy, but for me it allows me to relax to the point that sleep comes easily. The real killer feature is the measured dose of specific THC:CBD ratio that provides a real medicinal effect without getting too high. I think what I'm most excited about is that continued use hasn't minimized the effect the same way treatments like melatonin become ineffective after extended use.

[0] http://dosist.com/pen-calm/ [1] http://dosist.com/pen-relief/

>You could probably write software while on CBD.

It is possible to write software on CBD, THC, and others.

Don't need a medicinal card in California. Just walk in and buy. Or order with an app and get it delivered promptly to you.

Yup - getting easier to find at most head shops esp. in Manhattan.

Would CBD show on a typical 5-panel test which tests for THC?

Well it's a completely different molecule than THC, so no.

that's not the way screens work. definitely not the way immunoassay screens work, which is the most common screen that isn't just making shit up.

confirmatory testing, like a GC/MS or LC/MS/MS can tell them apart because they're different molecules, but the extraction processes for delta 9 THC can/will pick up all the similar molecules (delta 8, COOH, CBD, CBN, whatever).

that's necessary and good because they're not all psychoactive (the COOH in particular), so they've got to be separated out for forensic purposes.

It's not completely different. They appear to be identical in large portion. Check the diagrams at: https://patents.google.com/patent/US6630507B1/en

a cannabinoids immunoassay will tend to react with most of the cannabinoid-esque compounds. so, it's not a question of whether or not the test will "show" CBD, but rather, how much CBD is necessary to get the test to think there was an interesting/actionable amount of THC in the sample.

it works as a sort of linearish equation, where you add up all the compounds at different ratios, like 1.0THC + 0.5COOH + 0.05CBD + 0.05CBN + ... and if that adds up to "enough" then the test will trigger the testing lab to consider the screen positive.

at that point hopefully it goes over to confirmatory testing, where the LC/MS/MS separates all the various compounds apart, and lets the lab know that you had CBD in your system, but not THC.

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