Ask HN: Building a team in Berlin vs. the rest of Germany

I've recently been offered a position to become a technical lead of a new startup in Berlin, a city where I've worked as a developer for the last four years. For context, our product will involve large-scale data processing and analysis for heavy industry. I had assumed I would build up the team in Berlin, but talking to founders/CTOs/engineering managers in other companies here has convinced me to also consider other options.

My question is to anyone who has done a bit of hiring or managed a team in Berlin AND somewhere else. Was it easier/harder here, everything else being equal? Would you do it again? Are there hiring/personnel problems unique to Berlin that might have been invisible to me as a individual contributor?

We are particularly interested also in Munich due to some pre-existing customer relationships, but comparisons to anywhere else in Germany/Switzerland/Austria are welcome.