Refrigerating and air conditioning equipment can use plain hydrocarbon refrigerants such as propane and isobutane. US approval is fairly recent -- less than 10 years ago -- as you can see in this EPA table:
https://www.epa.gov/snap/substitutes-residential-and-light-c...
I believe that products using these low-GWP, zero-ODP refrigerants are marketed using the term "Greenfreeze."
https://cleantechnica.com/2008/09/29/first-greenfreeze-clima...