I would think it's self-evident that chemically (forcibly) modifying your perspective and the timbre of your subjective/emotional experience, a change that without chemical assistance would be slow, difficult to achieve, and often impossible, would not be entirely safe. But, safety isn't everything.

And speaking from personal experience, so can stressful activities like child birth. The human mind is complex, the best we can hope for is better educating people about mental health.

Sounds like a diagnosis to me.