For command-line applications, it opens up an interesting space. There was a post on HN a while ago: https://www.astrecipes.net/blog/2018/07/20/cmd-line-apps-wit... though the system requirements for compilation are at the moment very onerous.
> So you have no excuses not to build your CLI tools in Clojure now.
Well I do disagree with this part, see other sibling comments (not by me). I'm not even sure GraalVM is really production-ready, notwithstanding the potential licensing and long-term issues.
I do agree it's at least worth trying.
The big minefield is that you do not really know which libraries will go boom and where, as any place could make use of class loading.